A Pioneer in Advancing Measurement Technologies to Assure Biologic Drug Stability and Efficacy
The year was 2008. The second wave of therapeutic biological products was just around the corner. By now it was known that many of these products were susceptible to oxidative damage by residual hydrogen peroxide left over after aeration of the aseptic processing equipment and barrier system. How sensitive these products were to low concentrations of residual hydrogen peroxide was difficult to assess because there were no obvious measurement systems capable of quickly, accurately and precisely measuring vapor phase hydrogen peroxide below a few hundred parts per billion (ppb).
March 18, 2020
Three Ways To Ensure The Manufacturing Quality Of Your Therapeutic Biological Product
The most effective and valuable new therapeutic products today are biologics, including peptides, proteins, and antibody-drug conjugates (ADCs), as well as cells, cell-derived products, and gene therapies. Many of these products are susceptible to oxidative damage by trace levels of hydrogen peroxide.
March 11, 2020
Using Stable Carbon Isotopes to Track and Quantify Metabolic Fates of Evening Meals in Hummingbirds
Anyone who has watched a hummingbird frantically sip from a flower or feeder can appreciate how beautiful, hyperactive, and hungry these tiny birds are. It often seems that they are constantly on the move, fiendishly searching for and defending the flowers that contain the sugary nectar they depend on.
October 1, 2019
Real-Time Indoor Air Measurements of Ammonia Part 2: HOMEChem
In this second part of the 2-part blog series on Real-Time Indoor Air Measurements of Ammonia, we present a short summary of House Observations of Microbial and Environmental Chemistry (HOMEChem), part of the Indoor Chem Project (https://indoorchem.org/). Enjoy!
September 5, 2019
Real-Time Indoor Air Measurements of Ammonia Part 1: iCHEAR
In part 1 of this blog series, we explore how iCHEAR used a Picarro G2103 analyzer to provide real-time measurements of ammonia emissions to separate the contribution of exhaled and dermally emitted pollutants. What proportion of human emissions do you think can be measured and what proportion remain “missing”? Read on.
September 5, 2019
Measuring Climate Relevant Trace Gas Emissions in the Remote Highlands of Papua New Guinea
There are not many countries in the world left where you can truly say that they are blessed with intact native tropical forests. Of course we all know about the Amazon, but if we have a closer look it becomes clear that even the ‘Green hell’ as the Amazon basin has been labelled, is heavily affected by humans.
April 23, 2019
量化柬埔寨与越南周边湄公河三角洲的二氧化碳及甲烷外向通量
Picarro 公司,我们乐于听到研究小组如何将我们的系统运用到他们的项目中。来自英国赫尔大学的克里斯托弗•哈克尼 (Christopher Hackney) 和丹尼尔·帕森斯 (Daniel Parsons) 正与来自英国埃克塞特南安普顿大学、美国伊利诺伊大学、越南芹苴大学以及越南水资源研究南方研究所的合作伙伴在东南亚湄公河三角洲从事英国研究理事会暨牛顿基金资助项目(例如 http://www.stelar-s2s.org )的一系列研究工作。
September 25, 2018
仅 30 ppb 的气化过氧化氢 (VHP) 能够氧化和破坏药物
As biologics have supplanted small molecules as the dominant focus for many leading pharmaceutical companies, robust manufacturing processes for isolators and RABS continues to be an evolving process. In this environment, as the need for significantly better VHP monitoring has grown quickly, Picarro H 2 O 2 analyzers have increased in popularity.
August 29, 2018
加拿大不连续多年冻土中泥炭厌氧分解的实验性激发效应研究
Accelerated rates of warming and wildfires in northern regions of Canada will result in an extensive thaw of permafrost peatlands and peat plateaus. This could result in the potential release of greenhouse gases to the atmosphere. The Department of Renewable Resources at the University of Alberta, Canada have taken time to explain how they are using the Picarro G2201 -I analyzer and Small Sample Introduction Module (SSIM) to further investigate if substrate addition “primes” peat decomposition.
August 13, 2018
Measuring Small Volume Gas Concentrations with the Small Sample Introduction Module
The Picarro Small Sample Introduction Module (SSIM) is designed for processing small volumes of gas samples through a Picarro analyzer. Through a minor modification, we can now expand the functionality of the SSIM so that more accurate concentration measurements can be performed on both isotopic and concentration analyzers.
June 1, 2018
Please Attend Our Presentations at EGU 2018
If you are attending the 2018 EGU General Assembly from April 9 to 13 in Vienna, Austria, we hope you’ll attend Picarro-authored oral and poster presentations. Following is a list of the presentations with day, date and times, location, title, and authors: Oral Presentation EGU2018-11101 Fri, 13 Apr, 16:30, Room 0.88 Quantification of atmospheric for formaldehyde by near-infrared cavity ring-down spectroscopy Chris Rella et al.
March 29, 2018
Optimize the Precision and Accuracy of Seawater and High-Saline Water Stable Isotope Measurements
This is the third, and final, post in a three-part series that examines how Picarro analyzers, systems, and accessories ensure precise, accurate measurements of challenging seawater and high-saline water samples. The first post, Water Stable Isotope Measurements of Seawater , presents results from an inter-laboratory study designed to evaluate the quality of cavity ring-down spectroscopy (CRDS) derived measurements compared with the consistency and values of isotope ratio mass spectrometry (IRMS) measurements.
March 27, 2018